Dual role of PRMT1-dependent arginine methylation in cellular responses to genotoxic stress

We have recently shown that arginine methylation by protein arginine N-methyltransferase 1 (PRMT1) controls the response to cisplatin in ovarian cancer cells. In addition to increased methylation of chromatin proteins that favors senescence-associated secretory phenotype (SASP) activation, our study...

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Bibliografische Detailangaben

Hauptverfasser:	Roberto Giambruno, Tiziana Bonaldi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis Group 2020-07-01
Schriftenreihe:	Molecular & Cellular Oncology
Schlagworte:	arginine methylation mass spectrometry-based proteomics prmt1 sasp cisplatin stress granules llps phosphorylation
Online-Zugang:	http://dx.doi.org/10.1080/23723556.2020.1743808
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