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Investigation of the human-gut-kidney axis by fecal proteomics, highlights molecular mechanisms affected in CKD

Objective: The interplay of gut microbiota with the kidney system in chronic kidney disease (CKD), is characterized by increased concentrations of uric acid in the gut, which in turn, may increase bacterial uricase activity and may lead to the generation of uremic toxins. Nevertheless, knowledge on...

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Bibliografiske detaljer
Principais autores: Sonnal Lohia, Sophie Valkenburg, Rafael Stroggilos, Vasiliki Lygirou, Manousos Makridakis, Jerome Zoidakis, Francis Verbeke, Griet Glorieux, Antonia Vlahou
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2024-06-01
Serier:Heliyon
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Online adgang:http://www.sciencedirect.com/science/article/pii/S2405844024088595
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