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TGF-β drives pulmonary fibrosis through dual dysregulation of TNF pathway transcription and splicing

It is well known that TGF-β plays a key role in the progression of pulmonary fibrosis. However, how TGF-β/SMAD3 regulates downstream effector genes and its effect on alternative splicing in pulmonary fibrosis is still not fully understood. Here, we established a TGF-β-induced pulmonary fibrosis mode...

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Bibliographic Details
Main Authors: Peijun Wang, Mingliang Guo, Zhengxuan Zhang, Guojun Liu, Chuncheng Liu, Lu Cai, Hongyu Zhao
Format: Artigo
Language:Inglês
Published: Elsevier 2026-06-01
Series:European Journal of Cell Biology
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Online Access:http://www.sciencedirect.com/science/article/pii/S0171933526000051
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