Identification and Computational Analysis of <i>BRCA2</i> Variants in Mexican Women from Jalisco, Mexico, with Breast and Ovarian Cancer

Background: Breast and ovarian cancers (BC and OC) are prevalent malignancies in women globally, with germline variants in the <i>BRCA2</i> gene significantly increasing the risk of developing these cancers. Despite extensive studies, the frequency and impact of <i>BRCA2</i> variants in women from J...

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Principais autores:	Patricia Montserrat García-Verdín, José Elías García-Ortiz, Asbiel Felipe Garibaldi-Ríos, Ingrid Patricia Dávalos-Rodríguez, Sandra del Carmen Mendoza-Ruvalcaba, María Teresa Magaña-Torres, Luis E. Figuera, Mónica Alejandra Rosales-Reynoso, Cesar de Jesús Tovar-Jácome, Guillermo Moisés Zúñiga-González, Belinda Claudia Gómez-Meda, Blanca Miriam Torres-Mendoza, Raquel Villegas-Pacheco, René Gómez-Cerda, Julio César Cárdenas Valdez, Sergio Osvaldo Meza-Chavolla, Martha Patricia Gallegos-Arreola
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-10-01
coleção:	Medical Sciences
Assuntos:	<i>BRCA2</i> gene <i>BRCA2</i> pathogenic variants breast cancer ovarian cancer genetic variation computational biology
Acesso em linha:	https://www.mdpi.com/2076-3271/13/4/248
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