HLA-DRB1*15:01 is associated with a reduced likelihood of longevity in northern European men

Abstract Background Prior research on the genetics of human longevity has identified only a few robust associations. While these studies highlight the importance of metabolic processes for longevity, the contribution of immune genes, specifically those in the highly polymorphic human leukocyte antig...

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Hlavní autoři:	Nicolás Mendoza-Mejía, Daniel Kolbe, Onur Özer, Janina Dose, Guillermo G. Torres, Andre Franke, Marianne Nygaard, Almut Nebel
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-10-01
Edice:	Genome Medicine
Témata:	Human leukocyte antigen Longevity Genetic association study Ageing Immunogenetics
On-line přístup:	https://doi.org/10.1186/s13073-025-01554-1
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