Decoding macrophage heterogeneity in the pulmonary fibrosis lung cancer transition

Pulmonary fibrosis (PF) significantly increases the risk of lung cancer (LC), but the mechanisms underlying this transition remain unclear. This overview positions macrophage heterogeneity as a central node within the PF-LC continuum. First, we describe important subpopulations of profibrotic and pr...

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Autori principali:	Hanming Yu, Mengmeng Zhao, Qiuhong Li, Yuan Zhang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-03-01
Serie:	Frontiers in Immunology
Soggetti:	Epigenetic regulation macrophage heterogeneity metabolic reprogramming pulmonary fibrosis-associated lung cancer tumor microenvironment
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1787094/full
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