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Optimized models for design of efficient miR30-based shRNAs

Small hairpin RNAs (shRNAs) became an important research tool in cell biology. Reliable design of these molecules is essential for the needs of large functional genomics projects. To optimize the design of efficient shRNAs, we performed comparative, thermodynamic and correlation analyses of ~18,000...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Olga V Matveeva, Nafisa V Nazipova, Aleksey Y Ogurtsov, Svetlana A Shabalina
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2012-08-01
Rangatū:Frontiers in Genetics
Ngā marau:
Urunga tuihono:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00163/full
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