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Trilateral association of autophagy, mTOR and Alzheimer’s disease: Potential pathway in the development for Alzheimer’s disease therapy

The primary and considerable weakening event affecting elderly individuals is age-dependent cognitive decline and dementia. Alzheimer’s disease (AD) is the chief cause of progressive dementia, and it is characterized by irreparable loss of cognitive abilities, forming senile plaques having Amyloid B...

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Principais autores: Arunkumar Subramanian, T. Tamilanban, Abdulrhman Alsayari, Gobinath Ramachawolran, Ling Shing Wong, Mahendran Sekar, Siew Hua Gan, Vetriselvan Subramaniyan, Suresh V. Chinni, Nur Najihah Izzati Mat Rani, Nagaraja Suryadevara, Shadma Wahab
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-12-01
coleção:Frontiers in Pharmacology
Assuntos:
Alzheimer’s disease
mTOR pathway
dementia
autophagy
tau protein
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2022.1094351/full
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