Mechanistic Insights into the Capsule-Targeting Depolymerase from a Klebsiella pneumoniae Bacteriophage

ABSTRACT The production of capsular polysaccharides by Klebsiella pneumoniae protects the bacterial cell from harmful environmental factors such as antimicrobial compounds and infection by bacteriophages (phages). To bypass this protective barrier, some phages encode polysaccharide-degrading enzymes...

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Detalhes bibliográficos

Principais autores:	Rhys A. Dunstan, Rebecca S. Bamert, Matthew J. Belousoff, Francesca L. Short, Christopher K. Barlow, Derek J. Pickard, Jonathan J. Wilksch, Ralf B. Schittenhelm, Richard A. Strugnell, Gordon Dougan, Trevor Lithgow
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology 2021-09-01
coleção:	Microbiology Spectrum
Assuntos:	Klebsiella bacteriophages capsular polysaccharide cryo-EM depolymerase
Acesso em linha:	https://journals.asm.org/doi/10.1128/Spectrum.01023-21
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