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Quinazolin-4(3<i>H</i>)-ones and 5,6-Dihydropyrimidin-4(3<i>H</i>)-ones from β-Aminoamides and Orthoesters

Quinazolin-4(3<i>H</i>)-ones have been prepared in one step from 2-aminobenzamides and orthoesters in the presence of acetic acid. Simple 2-aminobenzamides were easily converted to the heterocycles by refluxing in absolute ethanol with 1.5 equivalents of the orthoester and 2 equivalents of acetic ac...

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Principais autores: Joshua T. Gavin, Joel K. Annor-Gyamfi, Richard A. Bunce
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2018-11-01
Series:Molecules
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Acceso en liña:https://www.mdpi.com/1420-3049/23/11/2925
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