Trigonelline mitigates bleomycin-induced idiopathic pulmonary fibrosis in mice

Objective: To evaluate the effect of trigonelline on bleomycin-induced idiopathic pulmonary fibrosis (IPF) and to explore its underlying mechanisms using network pharmacology. Methods: IPF was induced in C57BL/6 mice by a single intratracheal instillation of bleomycin (5 mg/kg). Trigonelline was adm...

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Principais autores:	Swapnil Gavhane, Chandrakant Gawli, Sachin Kumar, Biswajit Das, Gayatri Marathe, Vishal S. Patil, Harun M. Patel, Basavaraj Bommanahalli, Chanakya Nath Kundu, Chandragouda R. Patil
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wolters Kluwer Medknow Publications 2024-09-01
Series:	Asian Pacific Journal of Tropical Biomedicine
Assuntos:	trigonelline idiopathic pulmonary fibrosis antifibrotic bleomycin network pharmacology
Acceso en liña:	https://journals.lww.com/10.4103/apjtb.apjtb_414_24
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