Differential Pharmacodynamic Effects on Psoriatic Biomarkers by Guselkumab Versus Secukinumab Correlate with Long-Term Efficacy: An ECLIPSE Substudy

IL-23 is a cytokine produced by myeloid cells that drives the T helper 17 pathway and plays an essential role in the pathophysiology of plaque psoriasis. IL-23 activation initiates a cascade of cytokines subsequently inducing the expression of many psoriasis-related proteins. This study aimed to bet...

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Автори:	Andrew Blauvelt, Yanqing Chen, Patrick J. Branigan, Xuejun Liu, Samuel DePrimo, Brice E. Keyes, Monica Leung, Steven Fakharzadeh, Ya-Wen Yang, Ernesto J. Muñoz-Elías, James G. Krueger, Richard G. Langley
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Elsevier 2024-09-01
Серія:	JID Innovations
Предмети:	Guselkumab PD Psoriasis Secukinumab
Онлайн доступ:	http://www.sciencedirect.com/science/article/pii/S2667026724000444
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