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Reprogramming the anti-tumor immune response via CRISPR genetic and epigenetic editing

Precise clustered regularly interspaced short palindromic repeats (CRISPR)-mediated genetic and epigenetic manipulation of the immune response has become a promising immunotherapeutic approach toward combating tumorigenesis and tumor progression. CRISPR-based immunologic reprograming in cancer thera...

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Principais autores: Eric Alves, Shahama Taifour, Riccardo Dolcetti, Jonathan Chee, Anna K. Nowak, Silvana Gaudieri, Pilar Blancafort
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021-06-01
coleção:Molecular Therapy: Methods & Clinical Development
Assuntos:
immune response
clinical trials
CRISPR
genome editing
epigenome engineering
precision medicine
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2329050121000759
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