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Validation of the Epi2SensA Method Using the EpiDerm™ Model for Skin Sensitization Testing Under OECD TG442D

The Epi2SensA method is a method similar to the validated EpiSensA assay for assessing the skin sensitization potential of chemicals. The Epi2SensA protocol includes adaptation (changes to exposure conditions and the controls) for using an alternative reconstructed human epidermis (RhE) model, the E...

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Principais autores: Christian Pellevoisin, Hajime Kojima, Sebastian Hoffmann, Takao Ashikaga, Timothy Landry, Celina Romero, Kalyani Guntur, Mitchell Klausner, Jennifer Stadnicki, Helge Gehrke, Robert Mills-Goodlet, Niki Panousi, Victor J. Johnson, Gary R. Burleson, Kazuto Narita, Shigehiro Tachibana, Kohichi Kojima, Jan Markus, Alexander Armento
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2026-03-01
Serier:Toxics
Fag:
Epi2SensA
skin sensitization
reconstructed human epidermis
interlaboratory validation
OECD TG 442D
alternative testing methods
Online adgang:https://www.mdpi.com/2305-6304/14/4/295
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