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A randomized, double‐blind, single‐dose study to assess bioequivalence of MB02 biosimilar after manufacturing iteration and reference bevacizumab

Abstract To investigate and compare the pharmacokinetic (PK) profiles of MB02 products, before and after optimizing the manufacturing process, and reference bevacizumab to establish bioequivalence between them. In this randomized, double‐blind, single dose, parallel study, 114 healthy male volunteer...

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Principais autores: C. Schwabe, A. Cole, A. Espigares‐Correa, M. E. Beydon, A. Florez‐Igual, J. Queiruga‐Parada
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2023-04-01
Serier:Pharmacology Research & Perspectives
Fag:
bevacizumab
biosimilar
clinical trial
MB02
pharmacokinetics
safety
Online adgang:https://doi.org/10.1002/prp2.1070
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