Mathematical modelling of human P2X-mediated plasma membrane electrophysiology and calcium dynamics in microglia
Regulation of cytosolic calcium (Ca2+) dynamics is fundamental to microglial function. Temporal and spatial Ca2+ fluxes are induced from a complicated signal transduction pathway linked to brain ionic homeostasis. In this paper, we develop a novel biophysical model of Ca2+ and sodium (Na+) dynamics...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science (PLoS)
2021-11-01
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| Серии: | PLoS Computational Biology |
| Online-ссылка: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8584768/?tool=EBI |
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