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Physapruin A Induces Reactive Oxygen Species to Trigger Cytoprotective Autophagy of Breast Cancer Cells

<i>Physalis peruviana</i>-derived physapruin A (PHA) is a potent compound that selectively generates reactive oxygen species (ROS) and induces cancer cell death. Autophagy, a cellular self-clearance pathway, can be induced by ROS and plays a dual role in cancer cell death. However, the role of autop...

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Principais autores: Tzu-Jung Yu, Jun-Ping Shiau, Jen-Yang Tang, Chia-Hung Yen, Ming-Feng Hou, Yuan-Bin Cheng, Chih-Wen Shu, Hsueh-Wei Chang
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-07-01
Serier:Antioxidants
Fag:
withanolides
oxidative stress
autophagy
breast cancer
Online adgang:https://www.mdpi.com/2076-3921/11/7/1352
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