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Significant Variations in Double-Stranded RNA Levels in Cultured Skin Cells

Endogenous double-stranded RNA has emerged as a potent stimulator of innate immunity. Under physiological conditions, endogenous dsRNA is maintained in the cell nucleus or the mitochondria; however, if protective mechanisms are breached, it leaches into the cytoplasm and triggers immune signaling pa...

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Principais autores: Shaymaa Sadeq, Suwalak Chitcharoen, Surar Al-Hashimi, Somruthai Rattanaburi, John Casement, Andreas Werner
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-01-01
coleção:Cells
Assuntos:
double-stranded RNA
pattern recognition receptor
innate immunity
J2 antibody
RNA sequencing
Acesso em linha:https://www.mdpi.com/2073-4409/13/3/226
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