The novel GlcNAc 6-phosphate dehydratase NagS governs a metabolic checkpoint that controls nutrient signaling in Streptomyces.

Streptomyces bacteria are renowned for their multicellular lifestyle and as Nature's medicine makers, producing the majority of the clinical antibiotics. A landmark event during early development is the lytic dismantling of the substrate mycelium. Degradation of the hyphal cell-wall leads to the acc...

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Detalhes bibliográficos

Principais autores:	Chao Li, Mia Urem, Ioli Kotsogianni, Josephine Lau, Chao Du, Somayah S Elsayed, Nathaniel I Martin, Iain W McNae, Patrick Voskamp, Christoph Mayer, Sébastien Rigali, Navraj Pannu, Jan Pieter Abrahams, Lennart Schada von Borzyskowski, Gilles P van Wezel
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2025-11-01
coleção:	PLoS Biology
Acesso em linha:	https://doi.org/10.1371/journal.pbio.3003514
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