SENP3 regulates the global protein turnover and the Sp1 level via antagonizing SUMO2/3-targeted ubiquitination and degradation

ABSTRACT SUMOylation is recently found to function as a targeting signal for the degradation of substrates through the ubiquitin-proteasome system. RNF4 is the most studied human SUMO-targeted ubiquitin E3 ligase. However, the relationship between SUMO proteases, SENPs, and RNF4 remains obscure. The...

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Egile Nagusiak:	Ming Wang, Jing Sang, Yanhua Ren, Kejia Liu, Xinyi Liu, Jian Zhang, Haolu Wang, Jian Wang, Amir Orian, Jie Yang, Jing Yi
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Oxford University Press 2015-10-01
Saila:	Protein & Cell
Gaiak:	SUMOylation ubiquitination SENP3 RNF4 Sp1 gastric cancer
Sarrera elektronikoa:	http://link.springer.com/article/10.1007/s13238-015-0216-7
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