Prospective evaluation of cerebrospinal fluid concentrations of β-Endorphin as a predictor of opioid use after scheduled cesarean delivery

Abstract Background Prior laboratory work indicates that lower endogenous opioid function is associated with greater analgesic and subjective responses to opioid analgesics. We evaluated whether preoperative cerebrospinal fluid (CSF) concentrations of the analgesic endogenous opioid β-Endorphin (BE)...

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Autori principali:	Amelie Pham, Sarah S. Osmundson, Alex Pedowitz, Nancy Wickersham, Laura L. Sorabella, Stephen Bruehl
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2025-12-01
Serie:	BMC Pregnancy and Childbirth
Soggetti:	Beta-Endorphin Cerebrospinal fluid Cesarean delivery Endogenous opioid Postoperative opioid use
Accesso online:	https://doi.org/10.1186/s12884-025-08613-w
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