Low-intensity blast induces acute glutamatergic hyperexcitability in mouse hippocampus leading to long-term learning deficits and altered expression of proteins involved in synaptic plasticity and serine protease inhibitors

Neurocognitive consequences of blast-induced traumatic brain injury (bTBI) pose significant concerns for military service members and veterans with the majority of “invisible injury.” However, the underlying mechanism of such mild bTBI by low-intensity blast (LIB) exposure for long-term cognitive an...

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Detalhes bibliográficos

Principais autores:	Shanyan Chen, Heather R. Siedhoff, Hua Zhang, Pei Liu, Ashley Balderrama, Runting Li, Catherine Johnson, C. Michael Greenlief, Bastijn Koopmans, Timothy Hoffman, Ralph G. DePalma, De-Pei Li, Jiankun Cui, Zezong Gu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2022-04-01
coleção:	Neurobiology of Disease
Assuntos:	Primary open-field blast Glutamatergic hyperexcitability Home-cage monitoring Label-free proteomic quantitation Chronic cognitive dysfunction
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0969996122000250
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