Novel non-coding FOXP3 transcript isoform associated to potential transcriptional interference in human regulatory T cells

CD4+ regulatory T cells (TREGS) are critical for immune tolerance and the transcription factor Forkhead Box P3 (FOXP3) plays a crucial role in their differentiation and function. Recently, an alternative promoter has been reported for FOXP3, which is active only in TREGS and could have profound impl...

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Detalhes bibliográficos

Principais autores:	Marcos Cases, Niclas Ritter, Hector Rincon-Arevalo, Sandy Kroh, Aysegül Adam, Marieluise Kirchner, Hanieh Moradian, Manfred Gossen, Maria Dzamukova, Artür Manukyan, Markus Landthaler, Christopher Kressler, Anja E. Hauser, Daniel P. Depledge, Julia K. Polansky, Hyun-Dong Chang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis Group 2025-12-01
coleção:	RNA Biology
Assuntos:	FOXP3 TREG alternative promoter transcript isoform transcriptional interference
Acesso em linha:	https://www.tandfonline.com/doi/10.1080/15476286.2025.2502719
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