APETx-Like Peptides from the Sea Anemone <i>Heteractis crispa</i>, Diverse in Their Effect on ASIC1a and ASIC3 Ion Channels

Currently, five peptide modulators of acid-sensing ion channels (ASICs) attributed to structural class 1b of sea anemone toxins have been described. The APETx2 toxin is the first and most potent ASIC3 inhibitor, so its homologs from sea anemones are known as the APETx-like peptides. We have discover...

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Autors principals:	Rimma S. Kalina, Sergey G. Koshelev, Elena A. Zelepuga, Natalia Y. Kim, Sergey A. Kozlov, Emma P. Kozlovskaya, Margarita M. Monastyrnaya, Irina N. Gladkikh
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2020-04-01
Col·lecció:	Toxins
Matèries:	sea anemone APETx-like toxins acid-sensing ion channels electrophysiology molecular modeling
Accés en línia:	https://www.mdpi.com/2072-6651/12/4/266
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