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Effect of hydroxyurea on the promoter occupancy profiles of tumor suppressor p53 and p73

<p>Abstract</p> <p>Background</p> <p>The p53 tumor suppressor and its related protein, p73, share a homologous DNA binding domain, and mouse genetics studies have suggested that they have overlapping as well as distinct biological functions. Both p53 and p73 are activated by genotoxic stress to regu...

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Principais autores: Lu Xin, Huang Vera, Jiang Yong, Wang Jean YJ
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2009-06-01
Series:BMC Biology
Acceso en liña:http://www.biomedcentral.com/1741-7007/7/35
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