Limitations of current GABA agonists in neonatal seizures: towards GABA modulation via the targeting of neuronal Cl- transport

Neonatal intensive care has advanced rapidly in the last 40 years, with dramatic decreases in mortality and morbidity; however, for neonatal seizures, neither therapies nor outcomes have changed significantly. Clinical and experimental studies indicate that seizures in neonates have long-term neurod...

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Hauptverfasser:	Arjun eKhanna, Brian Patrick Walcott, Kristopher T Kahle
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2013-06-01
Schriftenreihe:	Frontiers in Neurology
Schlagworte:	Bumetanide GABA Agonists Status Epilepticus seizure NKCC1 Temporal Lobe Epilepsy
Online-Zugang:	http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00078/full
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