Non-selective calcium channel blocker bepridil decreases secondary pathology in mice after photothrombotic cortical lesion.

Experimental studies have identified a complex link between neurodegeneration, β-amyloid (Aβ) and calcium homeostasis. Here we asked whether early phase β-amyloid pathology in transgenic hAPPSL mice exaggerates the ischemic lesion and remote secondary pathology in the thalamus, and whether a non-sel...

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Detalhes bibliográficos

Principais autores:	Anu Lipsanen, Stefanie Flunkert, Kristina Kuptsova, Mikko Hiltunen, Manfred Windisch, Birgit Hutter-Paier, Jukka Jolkkonen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2013-01-01
coleção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC3608597?pdf=render
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