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Evidence for osteocyte-mediated bone-matrix degradation associated with periprosthetic joint infection (PJI)

Osteomyelitis associated with periprosthetic joint infection (PJI) signals a chronic infection and the need for revision surgery. An osteomyelitic bone exhibits distinct morphological features, including evidence for osteolysis and an accelerated bone remodelling into poorly organised, poor-quality...

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Principais autores: RT Ormsby, AR Zelmer, D Yang, NJ Gunn, Y Starczak, SP Kidd, R Nelson, LB Solomon, GJ Atkins
Format: Artigo
Sprog:Inglês
Udgivet: Forum Multimedia Publishing LLC 2021-10-01
Serier:European Cells & Materials
Fag:
periprosthetic joint infection
osteomyelitis
osteocyte
osteoclast
osteocytic osteolysis
perilacunar remodelling
collagen
Online adgang:https://www.ecmjournal.org/papers/vol042/pdf/v042a19.pdf
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