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Acid ceramidase targeting pyruvate kinase affected trypsinogen activation in acute pancreatitis

Abstract Background Acute pancreatitis is the sudden inflammation of the pancreas. Severe cases of acute pancreatitis are potentially fatal and have no specific treatment available. Premature trypsinogen activation could initiate acute pancreatitis. However, the mechanism underlying premature trypsi...

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Bibliografiske detaljer
Principais autores: Juan Xiao, Wenying Zeng, Pengcheng Zhang, Yuan Zhou, Qiangqiang Fang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2022-09-01
Serier:Molecular Medicine
Fag:
Online adgang:https://doi.org/10.1186/s10020-022-00538-w
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