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Targeting the activin receptor 1C on CD4+ T cells for cancer immunotherapy

Activins, members of the TGF-beta superfamily, have been isolated and identified in the endocrine system, but have not been substantially investigated in the context of the immune system and endocrine-unrelated cancers. Here, we demonstrated that tumor-bearing mice had elevated systemic activin leve...

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Principais autores: Ying Zheng, Andriana Lebid, Liam Chung, Juan Fu, Xiaoxu Wang, Andrea Otrocol, Jelani C. Zarif, Hong Yu, Nicolas J. Llosa, Drew M. Pardoll
פורמט: Artigo
שפה:Inglês
יצא לאור: Taylor & Francis Group 2024-12-01
סדרה:OncoImmunology
נושאים:
Activin
cancer immunotherapy
Foxp3
iTregs
TILs
Acvr1c
גישה מקוונת:https://www.tandfonline.com/doi/10.1080/2162402X.2023.2297503
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