क्यूआर कोड

High-fat diet plus HNF1A variant promotes polyps by activating β-catenin in early-onset colorectal cancer

The incidence of early-onset colorectal cancer (EO-CRC) is rising and is poorly understood. Lifestyle factors and altered genetic background possibly contribute. Here, we performed targeted exon sequencing of archived leukocyte DNA from 158 EO-CRC participants, which identified a missense mutation a...

पूर्ण विवरण

में बचाया:
मुख्य लेखकों: Heyu Song, Ricky A. Sontz, Matthew J. Vance, Julia M. Morris, Sulaiman Sheriff, Songli Zhu, Suzann Duan, Jiping Zeng, Erika Koeppe, Ritu Pandey, Curtis A. Thorne, Elena M. Stoffel, Juanita L. Merchant
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Clinical investigation 2023-07-01
श्रृंखला:JCI Insight
विषय:
Gastroenterology
Genetics
ऑनलाइन पहुंच:https://doi.org/10.1172/jci.insight.167163
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