Formulation and In-Vitro, Ex-Vivo, and In-Vivo Evaluation of Mucoadhesive Buccal Tablets Containing Labetalol Hydrochloride for Enhancement of Systemic Bioavailability
Objective: Labetalol hydrochloride is an alpha/beta adrenoceptor blocker that undergoes comprehensive first pass-metabolism resulting in a low oral bioavailability. This study aimed to formulate and evaluate mucoadhesive buccal formulations of labetalol hydrochloride for enhancement of its bioavaila...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Helwan University, Faculty of Pharmacy
2022-01-01
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| Schriftenreihe: | Journal of Advanced Pharmacy Research |
| Schlagworte: | |
| Online-Zugang: | https://aprh.journals.ekb.eg/article_216012_94ba6001de182bd0f317edc7fa323550.pdf |
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