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Adherence to low-dose methotrexate in children with juvenile idiopathic arthritis using a sensitive methotrexate assay

Abstract Background Low-dose weekly methotrexate (MTX) is the mainstay of treatment in juvenile idiopathic arthritis. Unfortunately, a substantial part of patients has insufficient efficacy of MTX. A potential cause of this inadequate response is suboptimal drug adherence. The aim of this study was...

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Principais autores: Julia E. Möhlmann, Sytze de Roock, Annelies C. Egas, Evelien ter Weijden, Martijn J. H. Doeleman, Alwin D. R. Huitema, Matthijs van Luin, Joost F. Swart
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2024-05-01
Serier:Pediatric Rheumatology Online Journal
Fag:
Methotrexate
MTX
Juvenile idiopathic arthritis
JIA
Drug adherence
Adherence assay
Online adgang:https://doi.org/10.1186/s12969-024-00988-y
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