Regulation of Oncogenic Targets by the Tumor-Suppressive <i>miR-139</i> Duplex (<i>miR-139-5p</i> and <i>miR-139-3p</i>) in Renal Cell Carcinoma

We previously found that both the guide and passenger strands of the <i>miR-139</i> duplex (<i>miR-139-5p</i> and <i>miR-139-3p</i>, respectively) were downregulated in cancer tissues. Analysis of TCGA datasets revealed that low expression of <i>miR-139-5p</i> (<i>p</i> < 0.0001) and <i>miR-139-3p</...

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Detalhes bibliográficos

Principais autores:	Reona Okada, Yusuke Goto, Yasutaka Yamada, Mayuko Kato, Shunichi Asai, Shogo Moriya, Tomohiko Ichikawa, Naohiko Seki
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2020-12-01
coleção:	Biomedicines
Assuntos:	<i>miR-139-5p</i> <i>miR-139-3p</i> renal cell carcinoma (RCC) microRNA tumor suppressor paxillin (<i>PXN</i>)
Acesso em linha:	https://www.mdpi.com/2227-9059/8/12/599
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