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Replacing Lu-177 with Tb-161 in DOTA-TATE and PSMA-617 therapy: potential dosimetric implications for activity selection

Abstract Aim To explore the dosimetric effect of substituting Lu-177 with Tb-161 in targeted radionuclide therapy (TRT) using the registered tracers DOTA-TATE and PSMA-617. Methods Using established kinetic data for [177Lu]Lu-DOTA-TATE and [177Lu]Lu-PSMA-617, radiation absorbed doses to typical tumo...

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Váldodahkkit: Frederik A. Verburg, Erik de Blois, Stijn Koolen, Mark W. Konijnenberg
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: SpringerOpen 2023-11-01
Ráidu:EJNMMI Physics
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Liŋkkat:https://doi.org/10.1186/s40658-023-00589-w
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