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Spautin-1 inhibits the growth of diffuse large B-cell lymphoma by inducing mitochondrial damage-mediated PANoptosis and anti-tumor immunity

Abstract The prognosis of relapsed or refractory diffuse large B-cell lymphoma (DLBCL) is poor. Therefore, searching for new therapeutic agents is particularly important to improve therapeutic efficacy. Targeting the ubiquitin-proteasome system is a potential therapeutic strategy for treating DLBCL....

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Autori principali: Jingjing Wu, Yuan Deng, Yong Gao, Bin Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer 2025-08-01
Serie:Cancer Immunology, Immunotherapy
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Accesso online:https://doi.org/10.1007/s00262-025-04150-9
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