Impact of doxorubicin-loaded ferritin nanocages (FerOX) vs. free doxorubicin on T lymphocytes: a translational clinical study on breast cancer patients undergoing neoadjuvant chemotherapy

Abstract Despite the advent of numerous targeted therapies in clinical practice, anthracyclines, including doxorubicin (DOX), continue to play a pivotal role in breast cancer (BC) treatment. DOX directly disrupts DNA replication, demonstrating remarkable efficacy against BC cells. However, its non-s...

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Hlavní autoři:	Marta Sevieri, Francesco Andreata, Francesco Mainini, Lorena Signati, Francesca Piccotti, Marta Truffi, Arianna Bonizzi, Leopoldo Sitia, Claudia Pigliacelli, Carlo Morasso, Barbara Tagliaferri, Fabio Corsi, Serena Mazzucchelli
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2024-04-01
Edice:	Journal of Nanobiotechnology
Témata:	Ferritin nanocages Doxorubicin PBMC T cells Breast cancer
On-line přístup:	https://doi.org/10.1186/s12951-024-02441-4
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