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Mitochondrial apoptosis gene-based pathomics for ovarian cancer prognosis

Abstract This study developed and validated a mitochondrial apoptosis-related pathology transfer learning model (MAR-PTL) for ovarian cancer prognosis by integrating digital pathology features with mitochondrial apoptosis gene expression. We constructed a transfer learning framework combining deep l...

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Principais autores: Lan-hui Qin, Xiaofang Huang, Chongze Yang, Rui Song, Pei-yin Chen, Zijian Jiang, Weihui Xu, Guanzhen Zeng, Hong Chen, Liling Long
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2026-03-01
coleção:Scientific Reports
Assuntos:
Ovarian cancer
Mitochondrial apoptosis
Pathomics
Prognosis
Single-cell analysis
Acesso em linha:https://doi.org/10.1038/s41598-026-40121-5
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