Hematopoietic ABCA1 deletion promotes monocytosis and worsens diet-induced insulin resistance in mice

Low-grade chronic inflammation plays an important role in the pathogenesis of obesity-induced insulin resistance. ABCA1 is essential for reverse cholesterol transport and HDL synthesis, and protects against macrophage inflammation. In the present study, the effects of ABCA1 deficiency in hematopoiet...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Chongren Tang, Yuhua Liu, Wendy Yang, Carl Storey, Tim S. McMillen, Barbara A. Houston, Jay W. Heinecke, Renee C. LeBoeuf
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Elsevier 2016-01-01
Цуврал:	Journal of Lipid Research
Нөхцлүүд:	cholesterol adipose tissue macrophages high density lipoprotein obesity diabetes
Онлайн хандалт:	http://www.sciencedirect.com/science/article/pii/S002222752031405X
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!