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Bioluminescent optogenetic (BL-OG) activation of neurons during mouse postnatal brain development

Summary: Bioluminescent optogenetics (BL-OG) allows activation of photosensory proteins, such as opsins, by either fiberoptics or by administering a luciferin. BL-OG thus confers both optogenetic and chemogenetic access within the same genetically targeted neuron. This bimodality offers a powerful a...

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Principais autores: Emmanuel L. Crespo, Mansi Prakash, Andreas Bjorefeldt, William E. Medendorp, Nathan C. Shaner, Diane Lipscombe, Christopher I. Moore, Ute Hochgeschwender
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021-09-01
Serier:STAR Protocols
Fag:
Developmental biology
Microscopy
Model Organisms
Molecular Biology
Neuroscience
Biotechnology and bioengineering
Online adgang:http://www.sciencedirect.com/science/article/pii/S2666166721003749
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