Collagen Fragments Produced in Cancer Mediate T Cell Suppression Through Leukocyte-Associated Immunoglobulin-Like Receptor 1

The tumor microenvironment (TME) is a complex structure comprised of tumor, immune and stromal cells, vasculature, and extracellular matrix (ECM). During tumor development, ECM homeostasis is dysregulated. Collagen remodeling by matrix metalloproteinases (MMPs) generates specific collagen fragments,...

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Principais autores:	Saskia V. Vijver, Akashdip Singh, Eline T. A. M. Mommers-Elshof, Jan Meeldijk, Ronald Copeland, Louis Boon, Sol Langermann, Dallas Flies, Linde Meyaard, M. Inês Pascoal Ramos
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2021-10-01
Serija:	Frontiers in Immunology
Teme:	LAIR-1 collagen ECM - extracellular matrix T cells cancer immunotherapy
Online dostop:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.733561/full
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