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Adjudication of a primary trial outcome: Results of a calibration exercise and protocol for a large international trial

Background: Ascertainment of the severity of the primary outcome of upper gastrointestinal (GI) bleeding is integral to stress ulcer prophylaxis trials. This protocol outlines the adjudication process for GI bleeding events in an international trial comparing pantoprazole to placebo in critically il...

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Hlavní autoři: Deborah Cook, Adam Deane, Joanna C. Dionne, François Lauzier, John C. Marshall, Yaseen M. Arabi, M. Elizabeth Wilcox, Marlies Ostermann, Abdulrahman Al-Fares, Diane Heels-Ansdell, Nicole Zytaruk, Lehana Thabane, Simon Finfer
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2024-06-01
Edice:Contemporary Clinical Trials Communications
Témata:
Adjudication
Clinical trials
Gastrointestinal bleeding
Critical care
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2451865424000310
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