SEMA4D/PlexinB1 promotes AML progression via activation of PI3K/Akt signaling
Abstract Background Acute myeloid leukemia (AML) is the most common type of acute leukemia in adults. SEMA4D is a 150 kDa transmembrane protein that belongs to the IV class of the subfamily of semaphorin family. Previous studies have reported that SEMA4D is a multifunctional target in many solid tum...
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| Principais autores: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BMC
2022-07-01
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| Series: | Journal of Translational Medicine |
| Assuntos: | |
| Acceso en liña: | https://doi.org/10.1186/s12967-022-03500-w |
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