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Physiologically Based Pharmacokinetic (PBPK) Modeling for Predicting Brain Levels of Drug in Rat

One of the main obstacles in neurological disease treatment is the presence of the blood–brain barrier. New predictive high-throughput screening tools are essential to avoid costly failures in the advanced phases of development and to contribute to the 3 Rs policy. The objective of this work was to...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bárbara Sánchez-Dengra, Isabel Gonzalez-Alvarez, Marival Bermejo, Marta Gonzalez-Alvarez
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2021-09-01
Saila:Pharmaceutics
Gaiak:
Sarrera elektronikoa:https://www.mdpi.com/1999-4923/13/9/1402
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