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Zmynd10 drives centriole biogenesis and multiciliogenesis through the transcriptional regulation of E2f4

Abstract Multiciliated cells (MCCs) play a crucial role in various physiological processes, including cerebrospinal fluid flow, mucus clearance, and reproductive transport, by coordinating ciliary movement. Their differentiation is regulated by the Notch signaling pathway, along with its downstream...

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Autori principali: Zhiming Liu, Qin Wu, Zhenhai Zhou, Wen Tan, Junlong Zhong, Shuai Fan, Kai Cao, Lu Huang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2025-12-01
Serie:Scientific Reports
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Accesso online:https://doi.org/10.1038/s41598-025-27956-0
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