Combinatorial binding in human and mouse embryonic stem cells identifies conserved enhancers active in early embryonic development.
Transcription factors are proteins that regulate gene expression by binding to cis-regulatory sequences such as promoters and enhancers. In embryonic stem (ES) cells, binding of the transcription factors OCT4, SOX2 and NANOG is essential to maintain the capacity of the cells to differentiate into an...
Gardado en:
| Principais autores: | , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2011-12-01
|
| Series: | PLoS Computational Biology |
| Acceso en liña: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22215994/pdf/?tool=EBI |
| Tags: |
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|