Comparison of the efficacy of obinutuzumab versus rituximab combined with tacrolimus in the treatment of refractory membranous nephropathy

Abstract Background Primary membranous nephropathy (pMN) is characterized by a prolonged course, frequent relapses, and variable treatment responses. While obinutuzumab (OBI) demonstrates promising efficacy in B-cell depletion, its direct comparison with the combination regimen of rituximab (RTX) pl...

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Detalhes bibliográficos

Principais autores:	Yulong Zhang, Mengnan Guo, Qi Bian, Shuangxi Li, Jing Sun, Zhenyu Qin, Jing Xu, Rui Dong
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-05-01
coleção:	BMC Nephrology
Assuntos:	Refractory membranous nephropathy Obinutuzumab Rituximab Adverse events
Acesso em linha:	https://doi.org/10.1186/s12882-026-04958-2
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