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The FGD5-AS1/miR-142-5p/CDK5 axis promotes ESCC progression by regulating mitochondrial fission and mitophagy: insights from integrative bioinformatics and experimental analyses

Abstract Esophageal squamous cell carcinoma (ESCC) continues to pose a significant health challenge worldwide because of its poor prognosis and limited therapeutic options. To identify key regulators, we performed integrative bioinformatic approaches, such as differential expression analysis, weight...

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Hlavní autoři: Min Hou, Shan Chen, Huadong Yang, Qingmei Huang, Hongmei Zhan, Yan Gui
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2026-04-01
Edice:World Journal of Surgical Oncology
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On-line přístup:https://doi.org/10.1186/s12957-026-04338-y
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