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Unmasking the bias: Can diffusion-weighted imaging reliably assess glymphatic function in awake and anesthetized brain?

This study investigated whether magnetic resonance (MR) diffusivity parameters derived from diffusion-weighted imaging (DWI) can serve as biomarkers of glymphatic function in awake and anesthetized mice. Spectral apparent diffusion coefficient (ADC) analysis, obtained using an inverse Laplace transf...

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Kaydedildi:
Asıl Yazarlar: Ryszard Stefan Gomolka, Antonio Ladrón-de-Guevara, Søren Grubb, Lydiane Hirschler, Isabelle Strom, Pia Weikop, Matthias van Osch, Maiken Nedergaard, Yuki Mori
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2026-03-01
Seri Bilgileri:NeuroImage
Konular:
Diffusion-weighted MR imaging
Wakefulness
Anesthesia
Cerebral blood perfusion
Glymphatic transport
Online Erişim:http://www.sciencedirect.com/science/article/pii/S1053811926000790
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