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Faster Adaptation in Smaller Populations: Counterintuitive Evolution of HIV during Childhood Infection.

Analysis of HIV-1 gene sequences sampled longitudinally from infected individuals can reveal the evolutionary dynamics that underlie associations between disease outcome and viral genetic diversity and divergence. Here we extend a statistical framework to estimate rates of viral molecular adaptation...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Jayna Raghwani, Samir Bhatt, Oliver G Pybus
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2016-01-01
Cyfres:PLoS Computational Biology
Mynediad Ar-lein:https://doi.org/10.1371/journal.pcbi.1004694
Tagiau: Ychwanegu Tag
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